Target：Glut5

Fields：Carbohydrate digestion and absorption

Gene Name：SLC2A5

Protein Name：Solute carrier family 2 facilitated glucose transporter member 5

Human Gene Id：6518

Human Swiss Prot No：P22732

Mouse Swiss Prot No：Q9WV38

Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A5. AA range:31-80

Specificity：Glut5 Polyclonal Antibody detects endogenous levels of Glut5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC2A5;GLUT5;Solute carrier family 2, facilitated glucose transporter member 5;Fructose transporter;Glucose transporter type 5, small intestine;GLUT-5

Observed Band(KD)：55kD

Background： The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016],

Function：function:Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.,induction:By forskolin (in Caco-2 cells).,mass spectrometry: PubMed:11840567,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,tissue specificity:Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.,

Subcellular Location：Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A. .

Expression：Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.