Target：RNF41

Fields：Endocytosis

Gene Name：RNF41 FLRF NRDP1 SBBI03

Protein Name：E3 ubiquitin-protein ligase NRDP1 (EC 6.3.2.-) (RING finger protein 41)

Human Gene Id：10193

Human Swiss Prot No：Q9H4P4

Mouse Swiss Prot No：Q8BH75

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RNF41 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：34kD

Background： This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],

Function：function:Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins, such as ERBB3.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SIAH-type zinc finger.,subunit:Interacts with USP8 and ERBB3.,tissue specificity:Detected in ovary, testis and prostate.,

Subcellular Location：cytosol,

Expression：Detected in ovary, testis and prostate.