Target：RN-tre

Gene Name：USP6NL

Protein Name：USP6 N-terminal-like protein

Human Gene Id：9712

Human Swiss Prot No：Q92738

Mouse Swiss Prot No：Q80XC3

Immunogen：The antiserum was produced against synthesized peptide derived from human USP6NL. AA range:451-500

Specificity：RN-tre Polyclonal Antibody detects endogenous levels of RN-tre protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：USP6NL;KIAA0019;USP6 N-terminal-like protein;Related to the N-terminus of tre;RN-tre

Molecular Weight(Da)：94kD

Background：function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed.,

Function：function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed.,

Subcellular Location：Golgi apparatus. Cytoplasmic vesicle.

Expression：Widely expressed.