Target：RNF130

Gene Name：RNF130

Protein Name：E3 ubiquitin-protein ligase RNF130

Human Gene Id：55819

Human Swiss Prot No：Q86XS8

Mouse Gene Id：59044

Mouse Swiss Prot No：Q8VEM1

Rat Gene Id：652955

Rat Swiss Prot No：Q6Y290

Immunogen：The antiserum was produced against synthesized peptide derived from human RNF130. AA range:231-280

Specificity：RNF130 Polyclonal Antibody detects endogenous levels of RNF130 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RNF130;E3 ubiquitin-protein ligase RNF130;Goliath homolog;H-Goliath;RING finger protein 130

Observed Band(KD)：36kD

Background：ring finger protein 130(RNF130) Homo sapiens The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Function：function:May have a role during the programmed cell death of hematopoietic cells.,similarity:Contains 1 PA (protease associated) domain.,similarity:Contains 1 RING-type zinc finger.,

Subcellular Location：Membrane ; Single-pass type I membrane protein . Cytoplasm .

Expression：Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts.