Main InformationTargetSecretinHost SpeciesRabbitReactivityHuman, Rat, Mouse,ApplicationsWB, ELISA, IHCMW13kD (Observed)Conjugate/ModificationUnmodifiedDetailed InformationRecommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.SpecificityThis antibody detects endogenous levels of human SecretinPurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Storage-15°C to -25°C/1 year(Do not lower than -25°C)Concentration1 mg/mlMW(Observed)13kDModificationUnmodifiedClonalityPolyclonalIsotypeIgGAntigen&Target InformationImmunogen:Synthesized peptide derived from human SecretinSpecificity:This antibody detects endogenous levels of human SecretinGene Name:SCTProtein Name:SecretinOther Name:SecretinBackground:This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016],Function:Function:Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach.,online information:Secretin entry,similarity:Belongs to the glucagon family.,Cellular Localization:Secreted .Research Areas:>>Neuroactive ligand-receptor interaction ; >>Pancreatic secretion ; >>Bile secretion