Main Information

Target

Secretin

Host Species

Rabbit

Reactivity

Human, Rat, Mouse,

Applications

WB, ELISA, IHC

MW

13kD (Observed)

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity

This antibody detects endogenous levels of human Secretin

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Concentration

1 mg/ml

MW(Observed)

13kD

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Synthesized peptide derived from human Secretin

Specificity:

This antibody detects endogenous levels of human Secretin

Gene Name:

SCT

Protein Name:

Secretin

Other Name:

Secretin

Database Link:

Organism	Gene ID	SwissProt
Human	6343;	P09683;

Background:

This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016],

Function:

Function:Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach.,online information:Secretin entry,similarity:Belongs to the glucagon family.,

Cellular Localization:

Secreted .

Research Areas:

>>Neuroactive ligand-receptor interaction ;
>>Pancreatic secretion ;
>>Bile secretion