Target：SPIT2

Gene Name：SPINT2 HAI2 KOP

Protein Name：Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)

Human Gene Id：10653

Human Swiss Prot No：O43291

Mouse Swiss Prot No：Q9WU03

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SPIT2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：27kD

Background： This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Function：domain:This inhibitor contains two inhibitory domains.,function:Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.,similarity:Contains 1 BPTI/Kunitz inhibitor domain.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,tissue specificity:Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.,

Subcellular Location：Membrane ; Single-pass type I membrane protein .

Expression：Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.