Target：SPIT1

Fields：Transcriptional misregulation in cancer;Prostate cancer

Gene Name：SPINT1 HAI1 UNQ223/PRO256

Protein Name：Kunitz-type protease inhibitor 1 (Hepatocyte growth factor activator inhibitor type 1) (HAI-1)

Human Gene Id：6692

Human Swiss Prot No：O43278

Mouse Swiss Prot No：Q9R097

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SPIT1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：58kD

Background： The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Function：domain:This inhibitor contains two inhibitory domains.,function:Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MANSC domain.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,

Subcellular Location：Secreted.

Expression： Colon,Milk,Placenta,