Target：Septin 3

Fields：Bacterial invasion of epithelial cells;Shigellosis

Gene Name：SEPT3

Protein Name：Neuronal-specific septin-3

Human Gene Id：55964

Human Swiss Prot No：Q9UH03

Mouse Gene Id：24050

Mouse Swiss Prot No：Q9Z1S5

Rat Gene Id：56003

Rat Swiss Prot No：Q9WU34

Immunogen：The antiserum was produced against synthesized peptide derived from human SEPT3. AA range:136-185

Specificity：Septin 3 Polyclonal Antibody detects endogenous levels of Septin 3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SEPT3;SEP3;Neuronal-specific septin-3

Observed Band(KD)：41kD

Background：septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Function：function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific.,

Subcellular Location：Cytoplasm. Cytoplasm, cytoskeleton . Cell junction, synapse .

Expression：Brain-specific.