Target:RPRM
Fields:p53 signaling pathway
Gene Name:RPRM
Protein Name:Protein reprimo
Human Gene Id:56475
Human Swiss Prot No:Q9NS64
Mouse Swiss Prot No:Q9JJ72
Rat Swiss Prot No:Q5BJN9
Immunogen:Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity:RPRM Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):11kD
Background:function:May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex.,induction:By TP53/p53, following X-ray irradiation.,miscellaneous:'Reprimo' signifies stop/repress.,similarity:Belongs to the reprimo family.,
Function:function:May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex.,induction:By TP53/p53, following X-ray irradiation.,miscellaneous:'Reprimo' signifies stop/repress.,similarity:Belongs to the reprimo family.,
Subcellular Location:Cytoplasm . Membrane ; Single-pass membrane protein .
Expression: Lung,