Target：GPDA

Fields：Glycerophospholipid metabolism

Gene Name：GPD1

Protein Name：Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)

Human Gene Id：2819

Human Swiss Prot No：P21695

Mouse Swiss Prot No：P13707

Rat Swiss Prot No：O35077

Immunogen：Synthesized peptide derived from human protein . at AA range: 210-290

Specificity：GPDA Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：38kD

Background： This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],

Function：catalytic activity:sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.,enzyme regulation:Inhibited by zinc ions and sulfate.,similarity:Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.,subunit:Homodimer.,

Subcellular Location：Cytoplasm .

Expression：Expressed in liver (at protein level).