Target：RPOM

Gene Name：POLRMT

Protein Name：DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)

Human Gene Id：5442

Human Swiss Prot No：O00411

Mouse Swiss Prot No：Q8BKF1

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RPOM Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：135kD

Background： This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008],

Function：catalytic activity:Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.,similarity:Belongs to the phage and mitochondrial RNA polymerase family.,subunit:Interacts with TFB1M and TFB2M, leading to the stimulation of transcription.,

Subcellular Location：Mitochondrion .

Expression： Aorta endothelial cell,Brain,Liver,