Target：LPCT4
Fields：Glycerophospholipid metabolism;Ether lipid metabolism;Metabolic pathways
Gene Name：LPCAT4 AGPAT7 AYTL3 LPEAT2
Protein Name：Lysophospholipid acyltransferase LPCAT4 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransf
Human Gene Id：254531
Human Swiss Prot No：Q643R3
Mouse Swiss Prot No：Q6NVG1
Immunogen：Synthesized peptide derived from human protein . at AA range: 300-380
Specificity：LPCT4 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：57kD
Background： Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008],
Function：caution:Was originally (PubMed:16243729) thought to be a lysophosphatidic acid acyltransferase based on sequence similarity but the mouse ortholog has been shown to be a lysophosphatidylcholine acyltransferase.,function:Converts lysophosphatidylcholine (LPC) to phosphatidycholine in the presence of acyl-CoA.,pathway:Lipid metabolism; phospholipid metabolism.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,tissue specificity:Widely expressed. Expressed in uterus, thymus, pancreas, skeletal muscle, bladder, stomach, lung and testis.,
Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Expression：Widely expressed with predominant level in brain.
