Target：DCI

Fields：Fatty acid degradation

Gene Name：ECI1

Protein Name：Enoyl-CoA delta isomerase 1 mitochondrial

Human Gene Id：1632

Human Swiss Prot No：P42126

Mouse Swiss Prot No：P42125

Immunogen：Synthesized peptide derived from DCI . at AA range: c-terminal

Specificity：DCI Polyclonal Antibody detects endogenous levels of DCI protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ECI1;DCI;Enoyl-CoA delta isomerase 1, mitochondrial;3,2-trans-enoyl-CoA isomerase;Delta(3),Delta(2)-enoyl-CoA isomerase;D3,D2-enoyl-CoA isomerase;Dodecenoyl-CoA isomerase

Observed Band(KD)：30kD

Background： This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010],

Function：catalytic activity:(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.,function:Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the enoyl-CoA hydratase/isomerase family.,subunit:Homotrimer.,

Subcellular Location：Mitochondrion matrix .

Expression：Expressed in liver (at protein level).