Target：MRP-L21

Fields：Ribosome

Gene Name：MRPL21

Protein Name：39S ribosomal protein L21 mitochondrial

Human Gene Id：219927

Human Swiss Prot No：Q7Z2W9

Mouse Gene Id：353242

Mouse Swiss Prot No：Q9D1N9

Immunogen：The antiserum was produced against synthesized peptide derived from human MRPL21. AA range:131-180

Specificity：MRP-L21 Polyclonal Antibody detects endogenous levels of MRP-L21 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MRPL21;39S ribosomal protein L21; mitochondrial;L21mt;MRP-L21

Observed Band(KD)：23kD

Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the ribosomal protein L21P family.,

Subcellular Location：Mitochondrion .