Target：Rap 2B

Gene Name：RAP2B

Protein Name：Ras-related protein Rap-2b

Human Gene Id：5912

Human Swiss Prot No：P61225

Mouse Gene Id：74012

Mouse Swiss Prot No：P61226

Rat Gene Id：170923

Rat Swiss Prot No：P61227

Immunogen：The antiserum was produced against synthesized peptide derived from human RAP2B. AA range:98-147

Specificity：Rap 2B Polyclonal Antibody detects endogenous levels of Rap 2B protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAP2B;Ras-related protein Rap-2b

Observed Band(KD)：18kD

Background： This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008],

Function：domain:The effector domain mediates the interaction with RUNDC3A.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A.,

Subcellular Location：Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Associated with red blood cells-released vesicles.

Expression：Expressed in red blood cells (at protein level).