Target：TUSC2

Gene Name：TUSC2

Protein Name：Tumor suppressor candidate 2

Human Gene Id：11334

Human Swiss Prot No：O75896

Mouse Gene Id：80385

Mouse Swiss Prot No：Q9WVF8

Immunogen：The antiserum was produced against synthesized peptide derived from human TUSC2. AA range:41-90

Specificity：TUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TUSC2;C3orf11;FUS1;LGCC;PDAP2;Tumor suppressor candidate 2;Fusion 1 protein;Fus-1 protein;PDGFA-associated protein 2

Observed Band(KD)：12kD

Background： This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],

Function：function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,

Subcellular Location：mitochondrion,

Expression：Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.