Target：Wee 2

Fields：Cell cycle;Human immunodeficiency virus 1 infection

Gene Name：WEE2

Protein Name：Wee1-like protein kinase 2

Human Gene Id：494551

Human Swiss Prot No：P0C1S8

Mouse Swiss Prot No：Q66JT0

Immunogen：The antiserum was produced against synthesized peptide derived from human WEE2. AA range:151-200

Specificity：Wee 2 Polyclonal Antibody detects endogenous levels of Wee 2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：WEE2;WEE1B;Wee1-like protein kinase 2;Wee1-like protein kinase 1B;Wee1B kinase

Observed Band(KD)：60kD

Background：catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,

Function：catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,

Subcellular Location：Nucleus .

Expression：Expressed in oocytes (at protein level) (PubMed:29606300). May also be expressed in testis (PubMed:11029659).