Target：DHHC-15
Gene Name：ZDHHC15
Protein Name：Palmitoyltransferase ZDHHC15
Human Gene Id：158866
Human Swiss Prot No：Q96MV8
Mouse Swiss Prot No：Q8BGJ0
Immunogen：The antiserum was produced against synthesized peptide derived from human ZDHHC15. AA range:288-337
Specificity：DHHC-15 Polyclonal Antibody detects endogenous levels of DHHC-15 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：ZDHHC15;Palmitoyltransferase ZDHHC15;Zinc finger DHHC domain-containing protein 15;DHHC-15
Observed Band(KD)：38kD
Background： The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
Function：catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,disease:Defects in ZDHHC15 are the cause of mental retardation X-linked type 91 (MRX91) [MIM:300577]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,PTM:Autopalmitoylated.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Expressed in placenta, liver, lung, kidney, heart and brain.,
Subcellular Location：Golgi apparatus membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic density .
Expression：Expressed in placenta, liver, lung, kidney, heart and brain.
