Target:CD23
Fields:Hematopoietic cell lineage;Epstein-Barr virus infection
Gene Name:FCER2 CD23A CLEC4J FCE2 IGEBF
Protein Name:Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleav
Human Gene Id:2208
Human Swiss Prot No:P06734
Immunogen:Synthesized peptide derived from human CD23 AA range: 200-321
Specificity:The antibody can specifically recognize human CD23 protein.
Formulation:PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source:Mouse, Monoclonal/IgG1, kappa
Dilution:IHC 1:200-400. IF 1:50-200. ELISA 1:500-5000
Purification:The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Molecular Weight(Da):36kD
Background: The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
Function:function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form.,
Subcellular Location:Membranous
Expression: B-cell,Blood,