Target：CD2

Fields：Cell adhesion molecules;Hematopoietic cell lineage

Gene Name：CD2

Protein Name：T-cell surface antigen CD2

Human Gene Id：914

Human Swiss Prot No：P06729

Mouse Gene Id：12481

Mouse Swiss Prot No：P08920

Rat Gene Id：497761

Rat Swiss Prot No：P08921

Immunogen：Synthetic Peptide of CD2

Specificity：The antibody detects endogenous CD2 proteins.

Formulation：PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Source：Monoclonal, Mouse

Dilution：IHC 1:200. IF 1:50-200

Purification：The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CD2;SRBC;T-cell surface antigen CD2;Erythrocyte receptor;LFA-2;LFA-3 receptor;Rosette receptor;T-cell surface antigen T11/Leu-5;CD2

Molecular Weight(Da)：39kD

Background： The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],

Function：function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression：Expressed in natural killer cells (at protein level).