Target：HSP β2

Fields：Proteoglycans in cancer

Gene Name：HSPB2

Protein Name：Heat shock protein beta-2

Human Gene Id：3316

Human Swiss Prot No：Q16082

Mouse Gene Id：69253

Mouse Swiss Prot No：Q99PR8

Rat Gene Id：161476

Rat Swiss Prot No：O35878

Immunogen：The antiserum was produced against synthesized peptide derived from human HSPB2. AA range:121-170

Specificity：HSP β2 Polyclonal Antibody detects endogenous levels of HSP β2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HSPB2;Heat shock protein beta-2;HspB2;DMPK-binding protein;MKBP

Observed Band(KD)：24kD

Background： The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012],

Function：similarity:Belongs to the small heat shock protein (HSP20) family.,subunit:Associates specifically with myotonic dystrophy protein kinase (DMPK).,tissue specificity:Expressed preferentially in skeletal muscle and heart but not in the lens.,

Subcellular Location：Cytoplasm . Nucleus . Localizes to nuclear foci.

Expression：Expressed preferentially in skeletal muscle and heart but not in the lens.