Target：HSP A9

Fields：RNA degradation;Tuberculosis

Gene Name：HSPA9

Protein Name：Stress-70 protein mitochondrial

Human Gene Id：3313

Human Swiss Prot No：P38646/Q8N1C8

Mouse Gene Id：15526

Rat Gene Id：291671

Rat Swiss Prot No：P48721

Immunogen：The antiserum was produced against synthesized peptide derived from human GRP75. AA range:630-679

Specificity：HSP A9 Polyclonal Antibody detects endogenous levels of HSP A9 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HSPA9;GRP75;HSPA9B;Stress-70 protein; mitochondrial;75 kDa glucose-regulated protein;GRP-75;Heat shock 70 kDa protein 9;Mortalin;MOT;Peptide-binding protein 74;PBP74

Observed Band(KD)：75kD

Background： This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010],

Function：function:Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with FXN.,

Subcellular Location：Mitochondrion . Nucleus, nucleolus .

Expression： B-cell,Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain