Target：HoxD12

Gene Name：HOXD12

Protein Name：Homeobox protein Hox-D12

Human Gene Id：3238

Human Swiss Prot No：P35452

Mouse Gene Id：15432

Mouse Swiss Prot No：P23812

Immunogen：The antiserum was produced against synthesized peptide derived from human HOXD12. AA range:191-240

Specificity：HoxD12 Polyclonal Antibody detects endogenous levels of HoxD12 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HOXD12;HOX4H;Homeobox protein Hox-D12;Homeobox protein Hox-4H

Observed Band(KD)：28kD

Background： This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008],

Function：function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Abd-B homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,

Subcellular Location：Nucleus.

Expression： PCR rescued clones,