Target：hnRNP LL

Gene Name：HNRPLL

Protein Name：Heterogeneous nuclear ribonucleoprotein L-like

Human Gene Id：92906

Human Swiss Prot No：Q8WVV9

Mouse Gene Id：72692

Mouse Swiss Prot No：Q921F4

Immunogen：The antiserum was produced against synthesized peptide derived from human HNRPLL. AA range:241-290

Specificity：hnRNP LL Polyclonal Antibody detects endogenous levels of hnRNP LL protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HNRPLL;SRRF;BLOCK24;Heterogeneous nuclear ribonucleoprotein L-like;hnRNPLL;Stromal RNA-regulating factor

Observed Band(KD)：60kD

Background：heterogeneous nuclear ribonucleoprotein L like(HNRNPLL) Homo sapiens HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008],

Function：function:May bind RNA and play a role in mRNA processing.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.,

Subcellular Location：nucleus,membrane,viral nucleocapsid,intracellular ribonucleoprotein complex,

Expression：Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.