Target：SLIK4

Fields：Cell adhesion molecules

Gene Name：SLITRK4

Protein Name：SLIT and NTRK-like protein 4

Human Gene Id：139065

Human Swiss Prot No：Q8IW52

Mouse Swiss Prot No：Q810B8

Immunogen：Synthesized peptide derived from human protein . at AA range: 130-210

Specificity：SLIK4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：92kD

Background： This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Function：function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 18 LRR (leucine-rich) repeats.,tissue specificity:Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, gliobastomas and primitive neuroectodermal tumors.,

Subcellular Location：Membrane ; Single-pass type I membrane protein . Cell membrane .

Expression：Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors.