Target:SLIK2
Fields:Cell adhesion molecules
Gene Name:SLITRK2 CXorf2 KIAA1854 SLITL1 UNQ9197/PRO34756
Protein Name:SLIT and NTRK-like protein 2
Human Gene Id:84631
Human Swiss Prot No:Q9H156
Mouse Swiss Prot No:Q810C0
Immunogen:Synthesized peptide derived from human protein . at AA range: 250-330
Specificity:SLIK2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):92kD
Background: This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.[provided by RefSeq, Feb 2010],
Function:function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 14 LRR (leucine-rich) repeats.,tissue specificity:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, gliobastomas, gangliogliomas and primitive neuroectodermal tumors.,
Subcellular Location:Membrane ; Single-pass type I membrane protein . Cell membrane .
Expression:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.