Target：SLC43A1

Gene Name：SLC43A1

Protein Name：Large neutral amino acids transporter small subunit 3

Human Gene Id：8501

Human Swiss Prot No：O75387

Mouse Swiss Prot No：Q8BSM7

Immunogen：The antiserum was produced against synthesized peptide derived from human LAT3. AA range:231-280

Specificity：SLC43A1 Polyclonal Antibody detects endogenous levels of SLC43A1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC43A1;LAT3;PB39;POV1;Large neutral amino acids transporter small subunit 3;L-type amino acid transporter 3;Prostate cancer overexpressed gene 1 protein;Solute carrier family 43 member 1

Observed Band(KD)：61kD

Background： SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008],

Function：function:Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.,miscellaneous:Up-regulated in early prostate cancer development with highest expression level in seminomas of testicular germ cell tumors.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.,

Subcellular Location：Membrane ; Multi-pass membrane protein .

Expression：In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.