Target：Six2

Gene Name：SIX2

Protein Name：Homeobox protein SIX2

Human Gene Id：10736

Human Swiss Prot No：Q9NPC8

Mouse Gene Id：20472

Mouse Swiss Prot No：Q62232

Immunogen：Synthesized peptide derived from Six2 . at AA range: 30-110

Specificity：Six2 Polyclonal Antibody detects endogenous levels of Six2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SIX2;Homeobox protein SIX2;Sine oculis homeobox homolog 2

Observed Band(KD)：33kD

Background： This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. [provided by RefSeq, Dec 2008],

Function：function:May be involved in limb tendon and ligament development.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Strongly expressed in skeletal muscle.,

Subcellular Location：Nucleus .

Expression：Strongly expressed in skeletal muscle. Expressed in Wilms' tumor and in the cap mesenchyme of fetal kidney (at protein level).