Target：SIX4

Fields：Transcriptional misregulation in cancer

Gene Name：SIX4

Protein Name：Homeobox protein SIX4 (Sine oculis homeobox homolog 4)

Human Gene Id：51804

Human Swiss Prot No：Q9UIU6

Mouse Swiss Prot No：Q61321

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SIX4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：85kD

Background： This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010],

Function：PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,

Subcellular Location：Nucleus . Cytoplasm .