Target：SgK288
Gene Name：ANKK1
Protein Name：Ankyrin repeat and protein kinase domain-containing protein 1
Human Gene Id：255239
Human Swiss Prot No：Q8NFD2
Mouse Swiss Prot No：Q8BZ25
Immunogen：The antiserum was produced against synthesized peptide derived from human ANKK1. AA range:321-370
Specificity：SgK288 Polyclonal Antibody detects endogenous levels of SgK288 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：ANKK1;PKK2;SGK288;Ankyrin repeat and protein kinase domain-containing protein 1;Protein kinase PKK2;Sugen kinase 288;SgK288;X-kinase
Observed Band(KD)：84kD
Background： The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009],
Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 12 ANK repeats.,tissue specificity:Highly expressed in brain and weakly expressed in placenta and spinal cord.,
Expression：Highly expressed in brain and weakly expressed in placenta and spinal cord.
