Target：Sg III

Gene Name：SCG3

Protein Name：Secretogranin-3

Human Gene Id：29106

Human Swiss Prot No：Q8WXD2

Mouse Swiss Prot No：P47867

Rat Gene Id：116635

Rat Swiss Prot No：P47868

Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human SCG3. AA range:21-70

Specificity：Sg III Polyclonal Antibody detects endogenous levels of Sg III protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SCG3;Secretogranin-3;Secretogranin III;SgIII

Observed Band(KD)：53kD

Background：secretogranin III(SCG3) Homo sapiens The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Function：subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in brain, heart, kidney, liver and skeletal muscle.,

Subcellular Location：Cytoplasmic vesicle, secretory vesicle . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein . Secreted . Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. .

Expression：Expressed in brain, heart, kidney, liver and skeletal muscle.