Target：SFTPD

Fields：Phagosome

Gene Name：SFTPD COLEC7 PSPD SFTP4

Protein Name：Pulmonary surfactant-associated protein D (PSP-D) (SP-D) (Collectin-7) (Lung surfactant protein D)

Human Gene Id：6441

Human Swiss Prot No：P35247

Mouse Swiss Prot No：P50404

Rat Swiss Prot No：P35248

Immunogen：Synthesized peptide derived from human protein . at AA range: 290-370

Specificity：SFTPD Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：41kD

Background： The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015],

Function：function:Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.,miscellaneous:Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).,online information:Pulmonary surfactant protein SP-D,PTM:Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.,PTM:The N-terminus is blocked.,similarity:Belongs to the SFTPD family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 collagen-like domain.,subunit:Oligomeric complex of 4 set o

Subcellular Location：Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Expression：Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).