Target：Septin 14

Gene Name：SEPT14

Protein Name：Septin-14

Human Gene Id：346288

Human Swiss Prot No：Q6ZU15

Mouse Swiss Prot No：Q9DA97

Immunogen：The antiserum was produced against synthesized peptide derived from human SEPT14. AA range:341-390

Specificity：Septin 14 Polyclonal Antibody detects endogenous levels of Septin 14 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SEPT14;Septin-14

Observed Band(KD)：50kD

Background： SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922164]).[supplied by OMIM, Jul 2008],

Function：function:Involved in cytokinesis .,similarity:Belongs to the septin family.,

Subcellular Location：Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Perikaryon . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalizes with actin stress fibers (PubMed:17922164). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). .

Expression：Testis-specific (at protein level).