Target：Septin 1

Fields：Bacterial invasion of epithelial cells

Gene Name：SEPT1

Protein Name：Septin-1

Human Gene Id：1731

Human Swiss Prot No：Q8WYJ6

Mouse Gene Id：54204

Mouse Swiss Prot No：P42209

Rat Gene Id：293507

Rat Swiss Prot No：Q5EB96

Immunogen：The antiserum was produced against synthesized peptide derived from human SEPT1. AA range:181-230

Specificity：Septin 1 Polyclonal Antibody detects endogenous levels of Septin 1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SEPT1;DIFF6;PNUTL3;Septin-1;LARP;Peanut-like protein 3;Serologically defined breast cancer antigen NY-BR-24

Observed Band(KD)：41kD

Background：septin 1(SEPT1) Homo sapiens This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012],

Function：function:Involved in cytokinesis .,similarity:Belongs to the septin family.,subunit:May assemble into a multicomponent structure.,

Subcellular Location：Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.

Expression：Expressed at high levels in lymphoid and hematopoietic tissues.