Target:TCF-9
Gene Name:GCFC2
Protein Name:GC-rich sequence DNA-binding factor 2
Human Gene Id:6936
Human Swiss Prot No:P16383
Mouse Swiss Prot No:Q8BKT3
Immunogen:The antiserum was produced against synthesized peptide derived from human GCF. AA range:141-190
Specificity:TCF-9 Polyclonal Antibody detects endogenous levels of TCF-9 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GCFC2;C2orf3;GCF;TCF9;GC-rich sequence DNA-binding factor 2;GC-rich sequence DNA-binding factor;Transcription factor 9;TCF-9
Observed Band(KD):80kD
Background: The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008],
Function:function:Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.,sequence caution:Contaminating sequence. The N-terminus matches the 2q37.3 region.,similarity:Belongs to the GCF family.,tissue specificity:Widely expressed in tissues and cell lines.,
Subcellular Location:Nucleus, nucleoplasm . Nucleus, nucleolus .
Expression:Widely expressed in tissues and cell lines.