Target：HIBADH

Fields：Valine, leucine and isoleucine degradation;Metabolic pathways

Gene Name：HIBADH

Protein Name：3-hydroxyisobutyrate dehydrogenase mitochondrial

Human Gene Id：11112

Human Swiss Prot No：P31937

Mouse Gene Id：58875

Mouse Swiss Prot No：Q99L13

Rat Gene Id：63938

Rat Swiss Prot No：P29266

Immunogen：The antiserum was produced against synthesized peptide derived from human HIBADH. AA range:281-330

Specificity：HIBADH Polyclonal Antibody detects endogenous levels of HIBADH protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HIBADH;3-hydroxyisobutyrate dehydrogenase; mitochondrial;HIBADH

Molecular Weight(Da)：35kD

Background： This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011],

Function：catalytic activity:3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.,similarity:Belongs to the 3-hydroxyisobutyrate dehydrogenase family.,subunit:Homodimer.,

Subcellular Location：Mitochondrion.

Expression：Detected in skin fibroblasts.