Target：HHEX

Fields：Maturity onset diabetes of the young;Transcriptional misregulation in cancer

Gene Name：HHEX HEX PRH PRHX

Protein Name：Hematopoietically-expressed homeobox protein HHEX (Homeobox protein HEX) (Homeobox protein PRH)

Human Gene Id：3087

Human Swiss Prot No：Q03014

Mouse Swiss Prot No：P43120

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：HHEX Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：29kD

Background： This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008],

Function：developmental stage:Expressed during hematopoiesis.,function:Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Liver and promyelocytic leukemia cell line HL60.,

Subcellular Location：Nucleus .

Expression：Liver and promyelocytic leukemia cell line HL-60.