Target：GROγ
Fields：Cytokine-cytokine receptor interaction;Viral protein interaction with cytokine and cytokine receptor;Chemokine signaling pathway;NF-kappa B signaling pathway;NOD-like receptor signaling pathway;IL-17 signaling pathway;TNF signaling pathway;Alcoholic liver disease;Epithelial cell signaling in Helicobacter pylori infection;Legionellosis;Amoebiasis;Kaposi sarcoma-associated herpesvirus infection;Rheumatoid arthritis;Lipid and atherosclerosis
Gene Name：CXCL3
Protein Name：C-X-C motif chemokine 3
Human Gene Id：2921
Human Swiss Prot No：P19876
Mouse Swiss Prot No：Q6W5C0
Immunogen：The antiserum was produced against synthesized peptide derived from human GROgamma. AA range:58-107
Specificity：GROγ Polyclonal Antibody detects endogenous levels of GROγ protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：CXCL3;GRO3;GROG;SCYB3;C-X-C motif chemokine 3;GRO-gamma(1-73);Growth-regulated protein gamma;GRO-gamma;Macrophage inflammatory protein 2-beta;MIP2-beta
Molecular Weight(Da)：11kD
Background： This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014],
Function：function:Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.,online information:CXCL3 entry,PTM:N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
Subcellular Location：Secreted.
Expression： Histiocytic lymphoma,Lung,Peripheral blood monocyte,Placenta,
