Target：LPAAT-δ
Fields：Glycerolipid metabolism;Glycerophospholipid metabolism;Metabolic pathways;Phospholipase D signaling pathway
Gene Name：AGPAT4
Protein Name：1-acyl-sn-glycerol-3-phosphate acyltransferase delta
Human Gene Id：56895
Human Swiss Prot No：Q9NRZ5
Mouse Gene Id：68262
Mouse Swiss Prot No：Q8K4X7
Rat Gene Id：170919
Rat Swiss Prot No：Q924S1
Immunogen：The antiserum was produced against synthesized peptide derived from human AGPAT4. AA range:151-200
Specificity：LPAAT-δ Polyclonal Antibody detects endogenous levels of LPAAT-δ protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000;IHC 1:50-300
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：AGPAT4;1-acyl-sn-glycerol-3-phosphate acyltransferase delta;1-acylglycerol-3-phosphate O-acyltransferase 4;1-AGP acyltransferase 4;1-AGPAT 4;Lysophosphatidic acid acyltransferase delta;LPAAT-delta
Observed Band(KD)：44kD
Background： This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008],
Function：catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,
Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Expression：Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.
