Target:Cdk11A/B
Gene Name:CDK11A/CDK11B
Protein Name:Cell division protein kinase 11A/B
Human Gene Id:728642/984
Human Swiss Prot No:Q9UQ88/P21127
Immunogen:Synthesized peptide derived from Cdk11A/B . at AA range: 190-270
Specificity:Cdk11A/B Polyclonal Antibody detects endogenous levels of Cdk11A/B protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CDK11A;CDC2L2;CDC2L3;PITSLREB;Cyclin-dependent kinase 11A;Cell division cycle 2-like protein kinase 2;Cell division protein kinase 11A;Galactosyltransferase-associated protein kinase p58/GTA;PITSLRE serine/threonine-protein kinase C
Observed Band(KD):90kD
Background: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
Function:caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,
Subcellular Location:Cytoplasm. Nucleus.
Expression:Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.