Target：Cdk10

Gene Name：CDK10

Protein Name：Cyclin-dependent kinase 10

Human Gene Id：8558

Human Swiss Prot No：Q15131

Mouse Gene Id：234854

Mouse Swiss Prot No：Q3UMM4

Rat Gene Id：361434

Rat Swiss Prot No：Q4KM47

Immunogen：The antiserum was produced against synthesized peptide derived from human CDK10. AA range:51-100

Specificity：Cdk10 Polyclonal Antibody detects endogenous levels of Cdk10 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CDK10;Cyclin-dependent kinase 10;Cell division protein kinase 10;Serine/threonine-protein kinase PISSLRE

Observed Band(KD)：43kD

Background： The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,

Subcellular Location：Cytoplasm, cytoskeleton, cilium basal body .

Expression： Brain,Colon,Kidney,Lung,