Target：Cdc42EP4

Gene Name：CDC42EP4

Protein Name：Cdc42 effector protein 4

Human Gene Id：23580

Human Swiss Prot No：Q9H3Q1

Mouse Swiss Prot No：Q9JM96

Immunogen：The antiserum was produced against synthesized peptide derived from human BORG4. AA range:201-250

Specificity：Cdc42EP4 Polyclonal Antibody detects endogenous levels of Cdc42EP4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CDC42EP4;BORG4;CEP4;Cdc42 effector protein 4;Binder of Rho GTPases 4

Observed Band(KD)：36kD

Background： The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008],

Function：function:Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with CDC42 and RHOQ, in a GTP-dependent manner.,tissue specificity:Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.,

Subcellular Location：Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.

Expression：Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.