Target：GNL3L

Fields：Ribosome biogenesis in eukaryotes

Gene Name：GNL3L

Protein Name：Guanine nucleotide-binding protein-like 3-like protein

Human Gene Id：54552

Human Swiss Prot No：Q9NVN8

Mouse Swiss Prot No：Q6PGG6

Immunogen：The antiserum was produced against synthesized peptide derived from human GNL3L. AA range:71-120

Specificity：GNL3L Polyclonal Antibody detects endogenous levels of GNL3L protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GNL3L;Guanine nucleotide-binding protein-like 3-like protein

Observed Band(KD)：66kD

Background： The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],

Function：domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,function:Required for normal processing of ribosomal pre-rRNA. Required for cell proliferation. Binds GTP.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family.,

Subcellular Location：Nucleus, nucleolus .

Expression： Lung,Skin,