Target:Di-Ras1
Gene Name:DIRAS1
Protein Name:GTP-binding protein Di-Ras1
Human Gene Id:148252
Human Swiss Prot No:O95057
Mouse Swiss Prot No:Q91Z61
Immunogen:The antiserum was produced against synthesized peptide derived from human DIRA1. AA range:149-198
Specificity:Di-Ras1 Polyclonal Antibody detects endogenous levels of Di-Ras1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:DIRAS1;GBTS1;RIG;GTP-binding protein Di-Ras1;Distinct subgroup of the Ras family member 1;Ras-related inhibitor of cell growth;Rig;Small GTP-binding tumor suppressor 1
Observed Band(KD):22kD
Background: DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004],
Function:function:Displays low GTPase activity and exist predominantly in the GTP-bound form.,similarity:Belongs to the small GTPase superfamily. Di-Ras family.,tissue specificity:Highly expressed in heart and brain.,
Subcellular Location:Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Expression:Highly expressed in heart and brain.