Target：DIRA3

Gene Name：DIRAS3 ARHI NOEY2 RHOI

Protein Name：GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)

Human Gene Id：9077

Human Swiss Prot No：O95661

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：DIRA3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：25kD

Background： This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015],

Function：online information:NOEY2 entry,similarity:Belongs to the small GTPase superfamily. Di-Ras family.,tissue specificity:Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Expression：Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers.