Target：FGF-22

Fields：MAPK signaling pathway;Ras signaling pathway;Rap1 signaling pathway;Calcium signaling pathway;PI3K-Akt signaling pathway;Regulation of actin cytoskeleton;Pathways in cancer;Chemical carcinogenesis - receptor activation;Melanoma;Breast cancer;Gastric cancer

Gene Name：FGF22

Protein Name：Fibroblast growth factor 22

Human Gene Id：27006

Human Swiss Prot No：Q9HCT0

Mouse Gene Id：67112

Mouse Swiss Prot No：Q9ESS2

Immunogen：The antiserum was produced against synthesized peptide derived from human FGF22. AA range:71-120

Specificity：FGF-22 Polyclonal Antibody detects endogenous levels of FGF-22 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FGF22;Fibroblast growth factor 22;FGF-22

Observed Band(KD)：20kD

Background： The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Function：function:May be involved in hair development.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Interacts with FGFBP1.,

Subcellular Location：Secreted .

Expression： Placenta,