Target：FGF21

Fields：MAPK signaling pathway;Ras signaling pathway;Rap1 signaling pathway;Calcium signaling pathway;PI3K-Akt signaling pathway;Thermogenesis;Regulation of actin cytoskeleton;Pathways in cancer;Melanoma;Breast cancer;Gastric cancer

Gene Name：FGF21 UNQ3115/PRO10196

Protein Name：Fibroblast growth factor 21 (FGF-21)

Human Gene Id：26291

Human Swiss Prot No：Q9NSA1

Mouse Swiss Prot No：Q9JJN1

Immunogen：Synthesized peptide derived from human protein . at AA range: 90-170

Specificity：FGF21 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：22kD

Background： Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016],

Function：function:Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1, but not SLC2A4/GLUT4, expression.,similarity:Belongs to the heparin-binding growth factors family.,

Subcellular Location：Secreted .

Expression： Lung,