Target：N4BP1

Gene Name：N4BP1

Protein Name：NEDD4-binding protein 1

Human Gene Id：9683

Human Swiss Prot No：O75113

Mouse Swiss Prot No：Q6A037

Immunogen：The antiserum was produced against synthesized peptide derived from human N4BP1. AA range:383-432

Specificity：N4BP1 Polyclonal Antibody detects endogenous levels of N4BP1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：N4BP1;KIAA0615;NEDD4-binding protein 1;N4BP1

Observed Band(KD)：100kD

Background：PTM:Monoubiquitinated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the N4BP1 family.,subcellular location:In discrete circular structures.,subunit:Binds NEDD4.,tissue specificity:Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary.,

Function：PTM:Monoubiquitinated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the N4BP1 family.,subcellular location:In discrete circular structures.,subunit:Binds NEDD4.,tissue specificity:Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary.,

Subcellular Location：Cytoplasm, cytosol . Nucleus . Nucleus, nucleolus . Nucleus, PML body . Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated. .

Expression：Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary.