Target：Myomesin-2

Gene Name：MYOM2

Protein Name：Myomesin-2

Human Gene Id：9172

Human Swiss Prot No：P54296

Immunogen：The antiserum was produced against synthesized peptide derived from human MYOM2. AA range:612-661

Specificity：Myomesin-2 Polyclonal Antibody detects endogenous levels of Myomesin-2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MYOM2;Myomesin-2;165 kDa connectin-associated protein;165 kDa titin-associated protein;M-protein;Myomesin family member 2

Observed Band(KD)：165kD

Background： The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008],

Function：function:Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.,similarity:Contains 5 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with TTN/titin.,

Subcellular Location：Cytoplasm, myofibril, sarcomere, M line .

Expression： PNS,Skeletal muscle,