Target：MYO5B

Fields：Pathogenic Escherichia coli infection

Gene Name：MYO5B KIAA1119

Protein Name：Unconventional myosin-Vb

Human Gene Id：4645

Human Swiss Prot No：Q9ULV0

Mouse Swiss Prot No：P21271

Rat Swiss Prot No：P70569

Immunogen：Synthesized peptide derived from human protein . at AA range: 1120-1200

Specificity：MYO5B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：203kD

Background： The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009],

Function：disease:Defects in MYO5B are a cause of microvillus inclusion disease (MVID) [MIM:251850]. MVID is characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.,similarity:Contains 1 dilute domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 6 IQ domains.,subunit:Interacts with RAB11FIP2.,

Subcellular Location：Cytoplasm .

Expression： Brain,Colon,